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Our top choices for De Soto hotels

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
2.5 star property
Festus
7.8 out of 10, Good, (911)
"Vary clean"
United States
George
The price is AU$133
includes taxes & fees
19 Dec - 20 Dec
Comfort Inn Festus - St Louis South

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1005)
"Room was clean , staff was friendly !"
United States
Sally
The price is AU$92
includes taxes & fees
24 Dec - 25 Dec
Baymont Inn and Suites by Wyndham Farmington, MO

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 star property
Festus
9.4 out of 10, Exceptional, (700)
"Clean, spotless, great room, front desk staff was excellent! Parking great!"
United States
Rick
The price is AU$219
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very good, (886)
"Gave us an early arrival, very friendly desk staff, clean room"
United States
Jeanine
The price is AU$160
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very good, (612)
"Clean, friendly staff, quiet"
United States
Stacy
The price is AU$90
includes taxes & fees
24 Dec - 25 Dec
Super 8 by Wyndham Farmington

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (575)
"Clean, friendly staff enjoyed the stay"
United States
John
The price is AU$170
includes taxes & fees
24 Dec - 25 Dec
Crown Pointe Lodge, BW Signature Collection

Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (518)
"Clean room, friendly staff."
United States
William
The price is AU$197
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Farmington

The Conner House B&B

The Conner House B&B
3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (19)
"Wonderful folks that work there. Nice b&b in a quiet , scenic area."
United States
Bradley
The price is AU$217
includes taxes & fees
18 Dec - 19 Dec
The Conner House B&B

Quality Inn Farmington

Quality Inn Farmington
2.5 star property
Farmington
7.6 out of 10, Good, (862)
"The staff was friendly. We had a few issues with our stay but overall was good. Love there breakfast variety "
United States
edith
The price is AU$92
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn Farmington

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1002)
"Clean room, comfortable bed, free breakfast, dinner and drinks every night! We had a great stay, will definitely stay again!"
United States
Jacqueline
The price is AU$214
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites St. Louis Arnold

Baymont by Wyndham Festus

Baymont by Wyndham Festus
3.0 star property
Festus
6.8 out of 10, (921)
"Room was clean and comfortable for an overnight stay"
United States
Jack
The price is AU$139
includes taxes & fees
21 Dec - 22 Dec
Baymont by Wyndham Festus

Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (412)
"The staff was great!"
United States
Christopher
The price is AU$373
includes taxes & fees
17 Jan - 18 Jan 2026
Holiday Inn Express & Suites Farmington by IHG

Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast
2.5 star property
Maeystown
9.0 out of 10, Wonderful, (154)
"Hosts were excellent, very quiet and the breakfast was wonderful"
United States
Mark
The price is AU$211
includes taxes & fees
19 Dec - 20 Dec
Corner George Inn Bed & Breakfast

Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
2.0 star property
Bonne Terre
7.0 out of 10, Good, (538)
"The room was spacious and very clean. The parking was free and close to the entrance, excellent water pressure for the shower, and the staff was friendly and professional."
United States
Raymond
The price is AU$83
includes taxes & fees
27 Dec - 28 Dec
Super 8 by Wyndham Bonne Terre

Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (3)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
Tiny Houses of French Village

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
Arnold
9.4 out of 10, Exceptional, (1003)
"Always very pleasant staff!"
United States
Julie
The price is AU$157
includes taxes & fees
21 Dec - 22 Dec
Pear Tree Inn St. Louis Arnold

YMCA Trout Lodge

YMCA Trout Lodge
2.0 star property
Potosi
10.0 out of 10, Exceptional, (1)
"When checking in the staff was great. Stay was relaxing. Only downside was the carpeted floors in the bunk bed room. Appears the carpet under the beds has not been vacuumed in a bit with the dust, dead bugs and cobwebs. Had my wife not dropped an ear ring, would never have noticed so not a big thing. "
United States
Leonard
The price is AU$247
includes taxes & fees
27 Dec - 28 Dec
YMCA Trout Lodge

WoodSpring Suites St. Louis Arnold

WoodSpring Suites St. Louis Arnold
2.5 star property
Arnold
6.0 out of 10, (441)
"Location was great as was staff"
United States
Randall
The price is AU$141
includes taxes & fees
21 Dec - 22 Dec
WoodSpring Suites St. Louis Arnold

Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO
2.0 star property
Bonne Terre
6.8 out of 10, (25)
"Quick check-in; plenty of parking and the room was easy to find. Convenient, clean, casual, can’t complain. "
United States
Tim
The price is AU$95
includes taxes & fees
24 Dec - 25 Dec
Motel 6 Bonne Terre, MO
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Get away to De Soto! Enjoy the local cuisine and more.

Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

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Frequently asked questions

Where is the best place to stay in De Soto?
Pear Tree Inn St. Louis Arnold, located 23.1 mi (37.2 km) from the heart of De Soto, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Baymont Inn and Suites by Wyndham Farmington, MO and Drury Inn & Suites St. Louis Arnold. See all available top hotels, or vacation rentals in De Soto.
What are some of the best holiday rentals that De Soto has to offer?
Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.: This holiday home rental outside De Soto is located in a rural location, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in De Soto.
If I need to cancel my hotel reservation in De Soto, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.
What's the best dog-friendly accommodation option in De Soto?
What are some accommodation options with pools in De Soto?
Pear Tree Inn St. Louis Arnold: Features buffet, an outdoor pool and free self parking. Baymont Inn and Suites by Wyndham Farmington, MO and Drury Inn & Suites St. Louis Arnold are a couple of other choices that offer an on-site pool. View all hotels with pools in De Soto.
What is staying in De Soto like?
Visitors can enjoy all that De Soto has to offer, including its restaurants. In De Soto, there are 6 hotels and other accommodation options to choose from. Find out more about De Soto.
What should I see while I'm in De Soto?
Natural beauty is on display at Sunrise Lake Beach, Big River and Big Lake. A couple of additional sights to add to your itinerary are Washington State Park and Redfield's Flea Market. Take a look at what more there is to see and do in Expedia's De Soto guide.
What's the seasonal weather like in De Soto?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for De Soto is 1181 mm.

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